AGENDA | AGBT Precision Health

2026 AGBT Precision Health Meeting Agenda

Advances in Precision Therapeutics and AI in Genomic Medicine

11:00 a.m. - 7:30 p.m.

Hospitality Desk

1:00 p.m. - 4:00 p.m.

Pre-Conference Workshops

Join hands-on, expert-led sessions exploring tools, case studies, and practical approaches in precision health.

1:00 p.m. - 2:30 p.m.

Exposomics in Precision Health

Speakers:

Gary Patti, Washington University in St. Louis; Chirag Patel, Harvard University

Maayan Levy, Stanford University; Donghai Liang, Emory University

Moderator:

Stephen B. Montgomery, Stanford University

Workshop Description:

This workshop explores the growing role of exposomics in advancing precision health. Speakers will present applications spanning exposure measurement, disease mapping, and emerging therapeutic approaches, followed by a panel discussion.

Topics include technologies for assessing environmental exposures, progress toward a Human Exposome Project, the role of metabolites in therapy, and integrating exposure biology into precision health.

2:30 p.m. - 4:00 p.m.

Perspectives from Expert Stakeholders Across Interventional Genomics in Rare Disease

Speakers:

Petros Giannikopoulos, MD, Director, IGI Clinical Laboratory and Assistant Adjunct Professor of Laboratory Medicine, University of California, San Francisco

Olivia Kim-McManus, MD, Associate Clinical Professor, Neurosciences, University of California, San Diego

Moderator:

Katarzyna Ellsworth, PhD, FACMG, CGMB, Senior Director of Clinical Operations, Rady Children’s Institute for Genomic Medicine

Workshop Description:

This session covers the fast-moving field of precision genomic therapy for rare diseases, focusing on new developments in gene therapies, antisense oligonucleotides, and small molecule repurposing. It discusses how to incorporate genomic testing and data into personalized treatment plans, stressing the need for informatics, strong databases, and patient safety. Attendees will hear from geneticists, clinicians, researchers, patients, and regulators. After short presentations from each stakeholder, a fireside chat will allow for lively discussion about recent advances in creating and delivering effective treatments for people with rare conditions. Sponsored by Illumina.

Day One:

Theme: Foundations and Frontiers of Genomic Medicine
This evening grounds attendees in where genomic medicine stands today and where it is headed, setting a shared framework for advances in discovery, clinical application, and emerging technologies explored throughout the meeting

4:00 p.m. - 5:00 p.m.

Welcome Cocktail Hour

Session I:

Genomic Medicine Today and Tomorrow

This opening session reflects on the evolution of genomic medicine from foundational discoveries to present-day clinical impact. Speakers will examine key scientific and translational milestones while offering perspectives on the opportunities and challenges shaping the future of genomic and precision medicine.

5:00 p.m. - 5:15 p.m.

Opening Remarks, Welcome (Co-Chairs)

AGBT Precision Health Service Award

Recipient:

Michael Talkowski

5:15 p.m. - 5:45 p.m.

Richard Lifton, President, Rockefeller University

5:45 p.m. - 6:15 p.m.

Diana Bianchi, National Institutes of Health (former)

Prenatal Aneuploidy Screening and Incidental Detection of Cancer: Everything all at Once

6:15 p.m. - 6:45 p.m.

Dan Geschwind, University of California, Los Angeles

6:45 p.m. - 7:00 p.m.

Abstract Selected Talk

7:00 p.m. - 7:15 p.m.

Abstract Selected Talk

7:15 p.m. - 10:00 p.m.

Welcome Reception & Buffet Dinner

Day Three

Theme: From Insight to Impact in Rare Disease Genomic Medicine

Sessions focus on how advances in genomic medicine for rare disease move from discovery to real-world impact, spanning implementation in clinical settings, lived-patient experience, and translation into therapeutic development.

6:30 a.m. - 7:30 a.m.

Rise & Shine with AGBT (optional activity)

7:30 a.m. - 5:00 p.m.

Hospitality Desk

Session V:

Implementation of Precision Health and Clinical Impacts
This session examines how genomic insights are integrated into clinical care, with a focus on the roles of environment, nutrition, and early-life exposures in shaping disease risk and outcomes. Speakers will highlight emerging evidence and approaches that inform precision health strategies across the lifespan.

9:00 a.m. - 9:25 a.m.

Niall Lennon, Broad Institute of Harvard and MIT

Transformative technologies and clinical translation

9:25 a.m. - 9:50 a.m.

Kiran Musunuru, University of Pennsylvania

9:50 a.m. - 10:15 a.m.

Jenny Taylor, University of Oxford

10:15 a.m. - 10:40 a.m.

Theodore G. Drivas, University of Pennsylvania

Universal exome sequencing in critically ill adults: A diagnostic yield of 25% and race-based disparities in access to genetic testing

10:40 a.m. - 10:55 a.m.

Abstract Selected Talk

10:55 a.m. - 11:30 a.m.

Coffee Break

Session VI

Patient’s Perspective
This session brings precision health into human focus through the lived experience of a patient whose journey spans childhood cancer, survivorship, and active participation in genomic research. Joined by family and physician perspectives, the conversation explores how advances in genomic medicine shape care across time, from diagnosis and treatment to discovery and contribution, offering a moment of reflection on partnership, perseverance, and responsibility within the precision health community.

11:30 a.m. - 12:15 p.m.

Fireside Chat: A Life Shaped by Precision Health

Moderator:

Richard Wilson, Nationwide Children’s Hospital

12:15 p.m. - 1:45 p.m.

AGBT Lunch and Workshop

1:45 p.m. - 2:15 p.m.

Sponsor Talks

Session VII:

Advances in Therapeutic Discovery to Development
This session highlights the translation of genetic insights into therapeutic strategies for rare diseases. Talks will span functional studies, target discovery, and approaches to individualized treatment, illustrating how genomic research informs the development of precision therapies.

2:15 p.m. - 2:40 p.m.

Fyodor Urnov, Intellia and University of California-Berkeley

2:40 p.m. - 3:05 p.m.

Gonçalo Abecasis, Regeneron Genetics Center

3:05 p.m. - 3:30 p.m.

Nadav Ahituv, University of California-San Francisco

Functional characterization and therapeutic targeting of gene regulatory elements

3:30 p.m. - 3:45 p.m.

Abstract Selected Talk

3:45 p.m. - 4:00 p.m.

Abstract Selected Talk

4:00 p.m. - 4:15 p.m.

Closing Reflections

Meeting Co-Chairs:

Gail Jarvik, University of Washington, Seattle

Stephen Montgomery, Stanford University

Richard Wilson, Nationwide Children’s Hospital

6:00 p.m. - 9:00 p.m.

Sips & Science: A Sunset Dinner Cruise with AGBT
A crossover networking event bringing together attendees for an evening of relaxed, meaningful connection across institutions and specialties. This private yacht cruise includes dinner, drinks, and coastal sunset views, offering space to reflect on shared goals in advancing precision health and rare disease research. RSVP required; space is limited.

Day Two

Theme: Intelligence, Ethics, and Discovery in Genomic Medicine
Explore how advances in artificial intelligence and computational genomics are reshaping discovery and clinical application, while also examining the ethical, regulatory, and societal considerations that accompany their adoption in precision health.

7:30 a.m. - 7:30 p.m.

Hospitality Desk

7:30 a.m. - 9:00 a.m.

Breakfast

7:30 a.m. - 9:00 a.m.

AGBT Women’s Networking Breakfast (RSVP Required)
Join us for the inaugural Women’s Networking Event at Precision Health, a breakfast gathering focused on connection, mentorship, and shared experiences among women advancing science and precision health.

Session II:

AI for Genomic Medicine and Diagnostics
This session examines how artificial intelligence and advanced computational methods are reshaping the interpretation of genomic data and its application in clinical care. Talks will explore AI-driven approaches to variant interpretation, gene regulation, and disease biology, with particular attention to neurological disease, as well as the translation of genomic insights into actionable diagnostics and precision medicine strategies.

9:00 a.m. - 9:25 a.m.

Alexis Battle, Johns Hopkins University

9:25 a.m. - 9:50 a.m.

Sara Mostafavi, Genentech

9:50 a.m. - 10:15 a.m.

Marilyn Ritchie, Medical University of South Carolina

Big Data, Real Patients: AI/ML Strategies for EHR-Linked Biobanks

10:15 a.m. - 10:30 a.m.

Abstract Selected Talk

10:30 a.m. - 11:00 a.m.

Coffee Break

Session III:
11:00 a.m. - 11:50 a.m.

The Great Debate

As genomic medicine expands beyond specialized research settings into routine clinical care and large-scale data-sharing ecosystems, informed consent has become one of the field’s most pressing, and complex, challenges. In this signature Great Debate session, panelists will examine whether current consent models are fit for purpose and explore how emerging approaches, including digital and AI-enabled tools, could support more scalable, inclusive, and trustworthy participation in precision health.

Moderator:
Heidi Rehm, PhD, Broad Institute of MIT and Harvard; Massachusetts General Hospital

Panelists:

Kyle Brothers, Norton Children's Research Institute
Moran Snir, NEST
Jenny Taylor, Genomics England
Monica Wojcik, Boston Children's Hospital

11:50 p.m. - 12:30 p.m.

Next Gen Leadership Awards

Featuring awardees sharing their work and what the recognition means to them

12:30 p.m. - 2:00 p.m.

AGBT Lunch

1:00 p.m. - 2:00 p.m.

Dessert with Sponsors

2:05 p.m. - 2:50 p.m.

Sponsor Talks

Hear from industry partners advancing tools, platforms, and diagnostics supporting genomic innovation.

2:05 p.m. - 2:25 p.m.

Gold Sponsor: GeneDx

2:25 p.m. - 2:40 p.m.

Silver Sponsor: Nabsys

2:40 p.m. - 2:45 p.m.

Bronze Sponsor: Singular Genomics

Session IV:

Rare Disease Mechanisms and Innovation

This session explores recent advances in understanding and addressing rare genetic diseases, highlighting progress in disease mechanism discovery, functional genomics, and the translation of insights into therapeutic strategies. Speakers will share perspectives spanning clinical investigation, experimental models, and emerging approaches to treatment.

2:50 p.m. - 3:15 p.m.

Andrew Stergachis, University of Washington, Seattle

3:15 p.m. - 3:40 p.m.

Monica Wojcik, Boston Children's Hospital

3:40 p.m. - 4:00 p.m.

Poster Flash Talks

Brief Abstract-selected Poster Presentations

4:00 p.m. - 8:00 p.m.

Poster Session, Sponsor Reception, and Dinner

Hors d’oeuvres & Posters: 4:00 p.m – 6:00 p.m. 

Odd # Posters: 4:00 p.m. – 5:00 p.m.  
Even # Posters: 5:00 p.m. – 6:00 p.m.

Dinner & Desserts: 6:00 p.m. – 8:00 p.m. 

8:00 p.m. - 11:00 p.m.

Sponsor Social

2026 AGBT Precision Health Meeting Agenda

11:00 a.m. - 7:30 p.m.

1:00 p.m. - 4:00 p.m.

1:00 p.m. - 2:30 p.m.

2:30 p.m. - 4:00 p.m.

Day One:

4:00 p.m. - 5:00 p.m.

Session I:

5:00 p.m. - 5:15 p.m.​

5:15 p.m. - 5:45 p.m.

5:45 p.m. - 6:15 p.m.

6:15 p.m. - 6:45 p.m.

6:45 p.m. - 7:00 p.m.

7:00 p.m. - 7:15 p.m.

7:15 p.m. - 10:00 p.m.

5:00 p.m. - 5:15 p.m.